Abstract Bacteria-mediated cancer therapeutic strategies have attracted increasing interest due to their intrinsic tumor tropism.However, bacteria-based drugs face several challenges including the large size of bacteria and dense extracellular matrix, limiting their intratumoral delivery efficiency.In this study, we find that hyperbaric oxygen (HBO
Hypoxic/ischemic preconditioning (HPC/IPC) is an innate neuroprotective mechanism in which a number of endogenous molecules are known to be Decorating Ideas involved.Tuberous sclerosis complex 1 (TSC1), also known as hamartin, is thought to be one such molecule.It is also known that hamartin is involved as a target in the rapamycin (mTOR) signaling
Abstract The main objective of this study was to use deep learning, and convolutional neural networks (CNN), integrated with field geology to identify distinct lithological units.The Samadia-Tunduba region of the South Eastern Desert of Egypt was mapped geologically for the first time thanks to the use of processed developed CNN algorithms SALTY DO
Skin necrosis is the most common complication in total auricular reconstruction, which is mainly induced by vascular compromise and local stress concentration of the overlying skin.Previous studies generally emphasized the increase in the skin flap blood supply, while few reports considered the mechanical factors.However, skin injury is inevitable